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Results for "

organ transplant

" in MedChemExpress (MCE) Product Catalog:

7

Inhibitors & Agonists

3

Peptides

3

Inhibitory Antibodies

1

Natural
Products

Cat. No. Product Name Target Research Area
  • HY-P99257
    Bleselumab

    ASKP 1240; Anti-Human CD40 Recombinant Antibody

    		 Inhibitory Antibodies Inflammation/Immunology
    Bleselumab (ASKP 1240) is a human anti-CD40 monoclonal antibody (mAb). Bleselumab binds to human CD40 with high affinity (Kd:  0.24 nM). Bleselumab inhibits immune responses by blocking the interaction of CD40 with its ligand CD40L. Bleselumab prevents organ transplant rejection .
  • HY-P99152
    Muromonab

    		CD3 Inflammation/Immunology Cancer
    Muromonab is a monoclonal antibody targeting the CD3 receptor. Muromonab can block all cytotoxic T cell function. Muromonab also as an immunosuppressant agent given to reduce acute solid organ transplant rejection .
  • HY-P990025
    Empasiprubart

    ARGX-117

    		 Inhibitory Antibodies Inflammation/Immunology
    Empasiprubart (ARGX-117) a humanized inhibitory monoclonal antibody against complement C2. Empasiprubart prevents the formation of the C3 proconvertase and inhibits classical and lectin pathway activation upstream of C3 activation through binding to the Sushi-2 domain of C2. Empasiprubart exhibits pH- and calcium-dependent target binding. Empasiprubart prevents complement-mediated cytotoxicity in in vitro models for autoimmune hemolytic anemia and antibody-mediated rejection of organ transplants .

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